The US has wanted to break up or otherwise weaken/isolate Russia ever since almost immediately after the break-up of the USSR. That’s why it’s been expanding NATO ever-closer to Russia despite originally having sworn up & down never to move one inch eastward. The US couldn’t allow a Ukrainian government to stand that was friendly with Russia.

The US doesn’t want Europe and Russia to develop closer ties, because it doesn’t want the “Eurasian landmass” to ever cohere, because then it would become too self-sufficient and powerful for the US to control. Zbigniew Brzezinski laid this theory out when the Soviet Union fell. That’s why the US tried to convince Europe not to build Nord Stream 2 and then later not to turn it on, why Biden said he would “bring an end to it” if Russia invaded, and why they ultimately did bring an end to it.

The US also very much wants regime change or balkanization in Russia so it can resume its neocolonial plundering of it, which started under Yeltsin and ended under Putin. That’s why the US has a special hate for Putin in particular.

The US has been meddling in Europe ever since WWII, and Ukraine has an even longer fascist history.

• The U.S. Did Not Defeat Fascism in WWII, It Discretely Internationalized It
• History of Fascism in Ukraine: Part I, Part II, Part III, Part IV
• BBC, 2014: Ukraine underplays role of far right in conflict
• Human Rights Watch, 2014: Ukraine: Unguided Rockets Killing Civilians
• The Hill, 2017: The reality of neo-Nazis in Ukraine is far from Kremlin propaganda
• The Guardian, 2017: 'I want to bring up a warrior': Ukraine's far-right children's camp – video
• WaPo, 2018: The war in Ukraine is more devastating than you know
• Reuters, 2018: Ukraine’s neo-Nazi problem
• The Nation, 2019: Neo-Nazis and the Far Right Are On the March in Ukraine

While you're at it - also read up on Ukraine's "Orange Revolution". Since gaining its independence, the only way Ukraine has managed to install pro-western governments is by revolutions and coups.