If you have to you can, sometimes. But you should use alternatives, if possible.
Linux
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Linux is a family of open source Unix-like operating systems based on the Linux kernel, an operating system kernel first released on September 17, 1991 by Linus Torvalds. Linux is typically packaged in a Linux distribution (or distro for short).
Distributions include the Linux kernel and supporting system software and libraries, many of which are provided by the GNU Project. Many Linux distributions use the word "Linux" in their name, but the Free Software Foundation uses the name GNU/Linux to emphasize the importance of GNU software, causing some controversy.
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I mean. does o365 not work or you specifically want to run the exe's?
OnlyOffice has amazing compatibility with MS office formats and has an interface quite similar to the MS apps.
But if you want something a bit more feature rich, LibreOffice is the way to go.
I know it's not really what you asked for, but unless you want to run an ancient version of the office suite in Wine, it's the way to go. The MS office web apps on MS's website is also an option.
There's Onedriver to connect onedrive on Linux. Though it's been a while since I last used it.