In cases where you can know ahead of time your part is going to have a lot of repeated dimensions, i.e. it is symmetrical in one or more axes, or you know all the screw holes are going to be X diameter, or whatever, abuse the hell out of the equality constraint. That's what I do.
Select a bunch of lines and hit E. Now all those lines will always be the same length. Constrain just one of them to whatever length you need; all of them automatically follow suit.
Select a bunch of circles and hit E. Now all those holes will always be the same diameter. Constrain one, you get the idea.
This makes the task of, "Oh crap, I changed one tiny parameter and now I need to find it and change it again 3/7/15/etc. more times" evaporate instantly.