this post was submitted on 20 Feb 2025
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SneerClub

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Hurling ordure at the TREACLES, especially those closely related to LessWrong.

AI-Industrial-Complex grift is fine as long as it sufficiently relates to the AI doom from the TREACLES. (Though TechTakes may be more suitable.)

This is sneer club, not debate club. Unless it's amusing debate.

[Especially don't debate the race scientists, if any sneak in - we ban and delete them as unsuitable for the server.]

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[โ€“] mountainriver@awful.systems 11 points 22 hours ago (4 children)

We do not understand genetic code as code. We merely have developed some statistical relations between some part of the genetic code and some outcomes, but nobody understands the genetic code good enough to write even the equivalent of "Hello World!".

Gene modification consists of grabbing a slice of genetic code and splicing it into another. Impressive! Means we can edit the code. Doesn't mean we understand the code. If you grab the code for Donkey Kong and put it into the code of Microsoft Excel, does it mean you can throw barrels at your numbers? Or will you simply break the whole thing? Genetic code is very robust and has a lot of redundancies (that we don't understand) so it won't crash like Excel. Something will likely grow. But tumors are also growth.

Remember Thalidomide? They had at the time better reason to think it was safe then we today have thinking gene editing babies is safe.

The tech bros who are gene editing babies (assuming that they are, because they are stupid, egotistical and wealthy enough to bend most laws) are not creating super babies, they are creating new and exciting genetic disorders. Poor babies.

[โ€“] scruiser@awful.systems 6 points 15 hours ago

My understanding is that it is possible to reliably (given the reliability required for lab animals) insert genes for individual proteins. I.e. if you want a transgenetic mouse line that has neurons that will fluoresce under laser light when they are firing, you can insert a gene sequence for GCaMP without too much hassle. You can even get the inserted gene to be under the control of certain promoters so that it will only activate in certain types of neurons and not others. Some really ambitious work has inserted multiple sequences for different colors of optogenetic indicators into a single mouse line.

If you want something more complicated that isn't just a sequence for a single protein or at most a few protein, never mind something nebulous on the conceptual level like "intelligence" then yeah, the technology or even basic scientific understanding is lacking.

Also, the gene insertion techniques that are reliable enough for experimenting on mice and rats aren't nearly reliable enough to use on humans (not that they even know what genes to insert in the first place for anything but the most straightforward of genetic disorders).

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