this post was submitted on 14 Mar 2025
30 points (87.5% liked)

Science

3830 readers
598 users here now

General discussions about "science" itself

Be sure to also check out these other Fediverse science communities:

https://lemmy.ml/c/science

https://beehaw.org/c/science

founded 3 years ago
MODERATORS
you are viewing a single comment's thread
view the rest of the comments
[–] jet@hackertalks.com 0 points 8 hours ago* (last edited 8 hours ago) (1 children)

Let me introduce you to the The Carbohydrate-Insulin Model of Obesity - Beyond “Calories In, Calories Out”: https://doi.org/10.1001/jamainternmed.2018.2933 - Full Paper Here

TLDR: Insulin is the cause of almost all obesity you see. Carbohydrates drive blood sugar, blood sugar drives insulin, insulin drives weight gain. As a good example - T1Ds who don't take their insulin wont gain weight, no matter how much they eat.

[–] Tecovirimat@lemmy.dbzer0.com 3 points 3 hours ago

T1D who don’t take their insulin won’t gain weight because of vomiting and dying from diabetic ketoacidosis. Sorry, but is is a horrible example and whoever has DM type 1, please take your insulin. People are really dying from DKA and while it is hard to prevent some factors triggering DKA, compliance with insulin is definitely within our control.

Insulin (and to be more precise it’s baseline level and spikes) is one of the obesitygenic factors. But there are much more other factors there too, and reducing such complex multifactorial disease as obesity to insulin only is incorrect.

Otherwise good paper and thank you for adding full article!