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Have we accidentally bred some dogs for obesity? (arstechnica.com)

submitted 3 days ago by bestboyfriendintheworld@sh.itjust.works to c/science@mander.xyz

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[–] jet@hackertalks.com 0 points 3 days ago (1 children)

Insulin (and to be more precise it’s baseline level and spikes) is one of the obesitygenic factors. But there are much more other factors there too, and reducing such complex multifactorial disease as obesity to insulin only is incorrect.

I'd love to learn about the other factors. Can you illuminate a more correct understanding for me?

[–] Tecovirimat@lemmy.dbzer0.com 2 points 2 days ago (1 children)

Pathophysiology and risk factors are actually a pretty much half of the curriculum for a separate medical specialty. Here are some resources for a different depth levels of this rabbit hole:

Basic level: https://www.cdc.gov/obesity/risk-factors/risk-factors.html

Moderate to deep:

Obesity Pillars journal (open access) https://www.sciencedirect.com/journal/obesity-pillars
decent book: Handbook of Obesity 4th edition Vol 1 by George A. Bray and Claude Bouchar, available free on Anna’s Archive or can be bought on Amazon

Too deep (mostly for medical professionals) and more expensive: Course of lectures at Columbia university: https://www.ihn.cuimc.columbia.edu/education/continuing-medical-education-cme/columbia-cornell-obesity-medicine

[–] jet@hackertalks.com 1 points 2 days ago (1 children)

Thank you for the detailed reply.

The CDC link was brief as you indicated.

The CME lectures I can't afford.

I'll grab the handbook and look over it.

[–] Tecovirimat@lemmy.dbzer0.com 2 points 2 days ago

You are welcome. I liked the book and it has relatively recent info. Combining it with Obesity Pillars articles, you can get a very good understanding of modern views on pathophysiology of obesity.