this post was submitted on 13 Dec 2023
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Gen X, the meh generation
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I think Acetaminophen is the one that is likely to cause liver damage. It's fairly easy to exceed the processing capabilities of the liver with Acetaminophen and when that happens it causes liver damage. Also, since Acetaminophen is incorporated into so many other products like cough syrups and sinus and headache pills, people end up taking more than they realize because they take 2-3 products at a time. So Acetaminophen overdoses end up being surprisingly common.
https://www.goodrx.com/classes/nsaids/nsaids-ibuprofen-bad-liver-kidneys
Extended Ibuprofen use can cause kidney damage though.
Saw a stat recently that the #1 overdose (and overdose mortalities) seen in hospitals is acetaminophen, by a significant margin (orders of magnitude more than all opiods/opiates if I remember correctly, but don't quote me).
That's pretty SOBERING. And frustrating.
I know a teenager that died from an accidental acetaminophen overdose. He had a cold so took Tylenol cold, which has acetaminophen, and then because he had a headache too, he took some extra-strength "regular" Tylenol. Turns out he was one of a small number of people that are particularly sensitive to acetaminophen and taking essentially a double-dose killed him in his sleep.