Honestly I am dismayed we have this dumb ass reddit culture take hold. Not everything you disagree with must be ~~bannned from the sub~~ defederated immediately, your instance doesnt owe you a feed that's exactly how you like it. Defederation should be the last resort, since it entirely breaks communication and interaction between the instance's users.

Instead, use the client side blocking features to clean up your feed. Personally I have blocked over 80 communities and users because they are centered around topics or beliefs I dont want on my feed, I blocked two instances as well, but I can still read their user's comments and interact with their users outside the instances.

Defederating is just splintering the fediverse. Unless at all avoidable it shouldn't be done, in fact I chose my instance specifically because it defederates nobody but meta and illegal content such as gore and csam.