There can also be circumstances where you have to offer people a natural-looking key for general consumption. You can't put UUID's on car plates for example.

Often times, the first section of the UUID is unique enough. With certain UI design choices, one can encourage users to normally work with that, while having the full UUID available in a detail view or from a copy-button.

Another strategy I quite like, is to have the UUID as the definitely-always-unique identifier, and then have a separate name, which either the users can enter or we generate something like random adjective+animal.

But yes, neither of those strategies would work for car plates.