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Down to their heart cells, women and men have cardiovascular differences that matter
(www.statnews.com)
From a cursory glance, the article completely fails to explain what it means by "sex". Yes, there's differences in the cardiovascular health of men and women, but why? People tend to jump to the conclusion that it's something you are born with and that it is therefor tied to your AGAB, because they have the nonensical notion that "biological sex" is one reified, essentialist, concrete thing when it actually isn't.
The gender-specific symptoms the article describes are something that, like many other organic functions, can change within a matter of weeks when somebody goes on HRT. I used to have all the "chest-clutching man" symptoms of arterial hypertension and when i got on estrogen and anti-androgens, within less than a month they aligned with the "more diffuse" set of symptoms reported by women (which are actually not more diffuse at all, i feel the neck pain and shortness of breath on estrogen just as much as i felt the stabby pain on testosterone - doctors just tend to not recognize these symptoms). They also lessened a lot because a circulatory system on T is more suceptible to coronary heart disease than one on E.
Biological sex isn't a monolith and it is not immutable. People need to get that fact into their heads.