The geography of your home instance only matters if you decide you care about it.
No VPNs needed.
I'm using an account on a finnish instance, currently hosted in germany (used to be in Finland, but the admin moved to get a better deal on the hardware running it).
The only practical difference what instance your account is on makes, is what other instances it federates with.
That might matter depending on what you want to access, but it probably doesn't. Any reputable instance federates with all other reputable ones, while blocking the disreputable ones.
AFAIK, feddit.uk is a perfectly good choice.