Should be fine. All the memory will just need to run at the speed of the slower kit. Make sure you put the sticks in the correct channels for dual channel support. But yeah, maybe only do so when you actually need the memory.
this post was submitted on 30 Jun 2023
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Mixing RAM is OK. I've been running consumer PCs with mixed memory for years.
Better not put different sticks on the same channel, though. Depending on your MB you may need to set frequency manually to 1333, but most likely it will work without that.