That assumes that the particles are the same mass for the drug and human.

You could say a small percent mass.

Texas has a toll road with an 85 mph speed limit https://www.foxnews.com/auto/texas-opens-highway-with-85-mph-speed-limit-fastest-in-america-is-it-too-fast

Possibly, with tuning. Op would just have to be careful about reslivering. In my experience SMR drives really slow down when the CMR buffer is full.

Make sure you don't have SMR drives, if they are spinning drives. CMR drives are the I ly ones that should be used in a NAS, especially with ZFS. https://vermaden.wordpress.com/2022/05/08/zfs-on-smr-drives/