Ranvier

I just wanted to double check, and holy crap it's real:

www.leadstories.com/hoax-alert/2021/05/fact-check-this-oil-disposal-tip-was-in-popular-science-magazine-in-1963-but-it-was-not-a-good-idea-then-and-it's-not-a-good-idea-now.html

How to fuck up the water table in your surrounding area real fast.

Fun fact, doing this could create a monetary liability far in excess of the value of your home and property.

Age up the clown some too with some wrinkles, that clown is 78, almost as old as the other guy.

Also poor Krusty, being compared to Trump.

Then put me in with the 7 out of 10 Americans.

Is bribery and corruption an ideology?

Anti corruption laws, pushing for ranked choice voting, popular interstate vote compact, and fighting gerrymandering? Oh yeah, donated.

Horrible.

Just want to add another source here from an Israeli news source (Hareetz) also reporting all the major points from the above article.

https://archive.is/IZNtf https://www.haaretz.com/israel-news/2024-06-18/ty-article/.premium/israel-arrested-a-senior-doctor-in-gaza-six-days-later-he-died-in-a-shin-bet-facility/00000190-27eb-d14b-a999-27eb9aea0000

Probably not a surprise, but the suspicious uninvestigated deaths don't end there.

Lol, I did my best, typed it on a cell phone.

I agree it may have presented barriers for coordination the FDA and access to US markets. I haven't been able to dig deep into the Cuban studies, but just because something is labeled a phase 3 or phase 4 by the investigators doesn't necessarily mean it was done to the standards necessary for fda approval or in the correct context of current standard of care treatments in the US or who knows how many other issues. If it was fully ready for all markets as is and required no further investigations, and it was only the US FDA causing problems, I would expect it to have already been widely available in many other countries that don't have embargos with Cuba, like all of Europe. Currently it's only available in Cuba, Colombia, Bosnia and Herzegovina, Peru, and Paraguay.

Mostly though I didn't want someone to accidentally misread this and think it meant cure. I realize you did not say that, but it's just a common misreading I've noticed people make of the term cancer vaccines when they've been mentioned in popular media. Didn't want someone to drag their poor dying relative off to Paraguay thinking they're getting cured.

I agree the Cuban embargo is ridiculous, should be stopped, and is hurting both countries with no benefit to anyone (other than keeping a certain segment of voters in Florida happy).

It's also not a vaccine in the sense it's preventing cancer, it's for the treatment of cancer that is already there, specifically non small cell lung cancers (though it's being tested in other cancers that use the signaling mechanism being targeted). Not saying it's impossible that it could prevent cancer, just that it hasn't been tested in that way to the best of my knowledge.

There is some precedence for a vaccine like that though. The HPV vaccine for instance prevents HPV (and therefore hpv related cancers), but is also used as a treatment if an HPV related cancer develops.

Slight correction on that vaccine, the FDA doesn't authorize any drug for sale in the US that hasn't passed it's rigorous trials and gone through its approval process. It's currently being tested and has more trials ongoing right now. FDA will be able to approve it for sale if it passes its trials.

https://ascopubs.org/doi/10.1200/JCO.2023.41.16_suppl.9135

Also the word cancer vaccine kind of implies cure to some, but it's not by any means:

"MST was 10.83 months for vaccinated vs. 8.86 months for non-vaccinated. In the Phase III trial, the 5-year survival rate was 14.4% for vaccinated subjects vs. 7.9% for controls."

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346887/

So it might be a useful tool but just don't want to get hopes up unnecessarily. People who's immune system reacted to the vaccine the strongest did best, so current trials are focused on combining it with an immune checkpoint inhibitor drug to increase the immune response even more hopefully (and those drugs are already being used by themselves in cancer). These drugs block "checkpoints" in the immune system that would normally stop it from attacking things like yourself, which we kind of want it to do in cancer.

Not saying I support an embargo in Cuba, I don't, just don't want this comment to be inadvertently read as "Cuba has had the cure to lung cancer this whole time and you're not allowed to have it!" which isn't true.

Yes totally agree, there's no way this goes anywhere but worse somehow as long as Netanyahu remains in power. Hopefully elections (or just being hauled off to jail hopefully) push him out soon, for everyone's sake.

Yes not disputing at all that there's a proxy war (though Soviet Israeli relationship deteriorated long before that started with Soviets funding Israeli opponents since 1967), just that despite or partially because of this, Israel is closer to Russia than most western countries. Isreal doesn't want to upset Russia and give them more incentive to fund proxies against them, and some Israeli governments, like Netanyahu's especially, have helped provide cover for Russian actions. And Russia at times will often take surprisingly pro Israeli moves despite also funding proxies.

I don't think it would be impossible for Israel to switch alignment to Russia, and I think you would quickly see Russia providing cover and stopping any assistance with proxy conflict against them. It would be essentially accomplishing Russia's goal, so what would they have to fight Israel about anymore? Putin is a real politic great powers kind of leader who has no qualms about butchering civilians by the thousands. He's certainly not aligned with Iran because he's concerned about Palestinians. Israel becoming fully aligned with Russia would be accomplishing a 77 year in the making goal for the Soviet Union and Russia.