Every time people lament changes to the lore that amount to "not every member of species X is irredeemably evil" and claim the game is removing villains from it, I think how villains of so-caleld evil species fall into two cathegories: a) bland and boring and b)have something else, unrelated to their species going on for them, that makes them interesting.
I go with a setting where humans don't exist at all. The closest is Elves, and picking them comes with a whole host of implications, like needing twice as much food to survive and everyone assuming you're mega rich.