ADHD

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FDA approves multiple generics of Vyvanse (www.fda.gov)

submitted 1 year ago* (last edited 1 year ago) by azdle@news.idlestate.org to c/adhd@lemmy.world

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I count 13 generic manufacturers: search lisdexamfetamine on https://www.accessdata.fda.gov/scripts/cder/ob/search_product.cfm

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[–] LordOfTheChia@lemmy.world 7 points 1 year ago (1 children)

It's good in that it is more consistent during the day due to how it works and is absorbed by the body. For some that Adderall didn't work (or stopped working) Vyvanse was a good alternative, but at a much higher cost.

Not 100% on this source, but it's the only one which I found which described how Vyvance acts and why it's different from Adderall:

https://freebythesea.com/vyvanse-vs-adderall-whats-the-difference/

Adderall contains amphetamine salts directly while Vyvanse uses lisdexamfetamine as a “prodrug,” which gets converted into an active form in the body before it has any effects. This extra step makes its side effects less pronounced than those taking Adderall.

Adderall is more common as the patent expired in 2009 and it has had generics for over a decade. This has brought the 30-day supply price of Adderall to $10-$40. Meanwhile Vyvanse:

https://www.fiercepharma.com/pharma/u-s-faces-critical-moment-drug-pricing-reform-won-t-come-again-patients-for-affordable-drugs

Takeda, for its part, has ratcheted up the cost of ADHD superstar Vyvanse 19 times since its market debut in 2007. A bottle initially cost $341 before rebates and discounts, but after January’s hike, the list price is now an “astounding” $1,172, the patient group said.

[–] amtwon@lemmy.world 4 points 1 year ago* (last edited 1 year ago) (1 children)

Dr Barkley describes Vyvanse here (timestamped at 7:20):

https://youtu.be/dADuL-dVK80?t=440

[–] PipedLinkBot@feddit.rocks 2 points 1 year ago

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