this post was submitted on 07 Feb 2025
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Science

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Harvard researchers have found that M. morganii may contribute to depression by producing an inflammatory molecule.

  • Biochemical analyses reveal how the gut bacterium Morganella morganii may contribute to some cases of major depressive disorder.
  • The bacterium incorporates an environmental contaminant into one of its molecules, triggering inflammation — a known factor in disease development.
  • These findings suggest the contaminant could serve as a biomarker and further support the idea that major depressive disorder may have autoimmune connections.
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[–] zout@fedia.io 3 points 1 month ago (1 children)

places with the highest antibiotic use also has a correlated obesity rate

I agree that antibiotics should only be taken with extreme prejudice, but playing devils advocate you could also conclude that the antibiotics are working since illness correlates with malnutrition.

[–] dylanmorgan@slrpnk.net 9 points 1 month ago

Or some other correlated factor with no causative relationship. Like, obesity being tied to generally worse health outcomes so where antibiotics were less commonly used obese people died from infections more often. Like horse ownership correlating with better overall health, but the causative factor is “being wealthy enough to own horses.”