this post was submitted on 07 Jun 2025
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I think paracetamol/acetaminophen being barely perceptible is why I'll always feel safer with opioids, THC, or even NMDA antagonists like ketamine in a pinch--as someone who is extremely informed with this particular subject.
I blame autism.
If a compound is barely effective, causes liver damage (particularly with other compounds metabolised in the liver), and has a bunch of negative interactions.. sorry, it's garbage. I genuinely would rather go darknet than CVS or Walgreens, and test for purity. Besides, dealers are generally way cooler than corpos anyway.
I hope that nobody takes it as an invitation, though--I said I'm informed. If you're not informed, don't.
I will add this; Paracetamol? Almost placebo. Phenylephrine? Actually placebo. Guaifenesin? Placebo if taken orally. Practically the entire counter is placebo, except for the antihistamines (first/second generation like diphenhydramine/Benadryl and cetirizine/Zyrtec) and nasal cleaners and such. With that in mind, I would encourage people to research absolutely everything they ingest, regardless of how safe the product may seem.
They are certainly not 100% safe.
This should go without saying (probably preaching to a choir), but legal ≠ safe, indeed. Still waiting on that thesaurus to prove me wrong. It's been 3 years.
Stay smart, and stay safe.
There is a brand mixing acetylsalicylic acid and koffein which works wonders as a quick relief for migraine while my standard naproxen usually requires a few hours of darkness to start working, so I can't agree that all over the counter meds are garbage. I can't refute your placebo claims since the effect cant be measured by myself
Shoot, I forgot aspirin! It actually is a genuinely effective painkiller. Mixed with caffeine, and you pretty much have Excedrin. My mother has very bad migraines, and it is true that this formula just works, for some reason.
Excedrin is a good product. If you have a migraine, I'd suggest taking it. I will add that my mother seems addicted to it, though--taking it on the daily multiple times, even if a headache is mild.
Be careful!