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tweet by Johann Hari: The core of addiction is not wanting to be present in life, because pour life is too painful a place to be. This is why imposing more pain or punishment on a person with an addiction problem actually makes their addiction worse.
I take acid for a week straight during my birthday week and by the third or fourth day I'm not really experiencing much. Any psychedelic you take will have a very minuscule effect after a 3 day bender because your serotonin levels are very depleted. Personally I find shrooms just make me too emotional and I find the trips to be a little short so I much more prefer acid over any drug.
I do build a tolerance but I'm still 3xperienceing it by the 4th day. Shrooms r easier for me to talk abt cause I have more experience but got shrooms I can trip for maybe 3 weeks daily without any tolerance and I'm not entirely sure if I had tolerance at that point or was just getting more used to the situation
Edit: psychedelics don't deplete serotonin they attach to serotonin receptors. Mdma depletes serotonin