If the hero just minded his own business and did nothing, no one dies and his wife is never in danger but millions of dollars worth of bonds are stolen. It's a fair trade off, and might have even saved their marriage.

The Day Of The Jackal

Based on a book with no actual heroes. Just a cold-blooded assassination attempt. This isn't the type of movie I'm referring to, though I should have said "almost every single movie..." or "hero movies".

Rope

Uh...yeah...

In the play, two homosexual college students become fascinated by their philosophy professor’s ideas about the “innate superiority” of some people over others. Convinced they have found a victim who is inferior to them, they murder him, conceal his body in an unlocked trunk in their apartment, and then throw a dinner party with the trunk as the brazen centerpiece of the living room.

That's just a whole lot of fucked up. No heroes there, except maybe someone not realizing they are friends with psychopaths that have a dead body in their living room.

Seven Samurai

The heroes lose 4 of their own. I'll give you this one, this is the most realistic depiction of a hero movie.

The Martian

Poor mission planning. They can monitor, predict, and plan for dust storms on Mars today. But in the future, all that goes out the window when humans are involved? This entire scenario depends on someone not doing their job properly.