The instance seems to be mostly right wing trolls. I know defederating is unpopular but I don't think much is to be lost in this case and it can save the mods some headaches.
Edit: the response on exploding-heads.com to my reporting of transphobia. Courtesy of the "second in command"
I'm not blocking you; had you been replying to what I said?
also being blocked from an instance doesn't mean you're suddenly not able to use the Fediverse; it just means that that instance doesn't want to associate with yours
this can be fixed by just moving to another instance, or (in this case) getting rid of the alt-right shit
Defederation isn't an attack on free speech; it's a group saying that they don't want to interact with you; freedom of expression doesn't mean everyone must listen