this post was submitted on 01 May 2024
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The Environmental Protection Agency unveiled a proposal this week to ban a controversial pesticide that is widely used on celery, tomatoes and other fruits and vegetables.

The EPA released its plan on Tuesday, nearly a week after a ProPublica investigation revealed the agency had laid out a justification for increasing the amount of acephate allowed on food by removing limits meant to protect children’s developing brains.

But rather than banning the pesticide, as the European Union did more than 20 years ago, the U.S. Environmental Protection Agency recently proposed easing restrictions on acephate.

The federal agency’s assessment lays out a plan that would allow 10 times more acephate on food than is acceptable under the current limits. The proposal was based in large part on the results of a new battery of tests that are performed on disembodied cells rather than whole lab animals. After exposing groups of cells to the pesticide, the agency found “little to no evidence” that acephate and a chemical created when it breaks down in the body harm the developing brain, according to an August 2023 EPA document.

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[–] CosmicCleric@lemmy.world 0 points 6 months ago* (last edited 6 months ago)

The thing is, typically you are way way more likely to see results at high concentrations in isolated cells vs in an animal or human at more reasonable exposure rates, so you typically only elevate to animal testing once you’ve shown some pathway of effect in isolated cells.

Fair enough, wasn't aware of the pathway/elevation technique, as you described it.

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