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Never change a running system. Even small changes may have unexpected consequences, if the machine is as complex as our bodies...
Counterpoint: the cable management of the human body is fucked
90 millions years of evolution, or you: who knows better?
It looks funny on pictures, but i bet everything would go south if you would straighten it out or reorganize it.
If you don't know the intend why it looks as it currently looks i would not touch it. even if you know why it looks like that and you can somehow compensate those effects, i would not do this on my own body for the first time...
I think one thing I would change is that the nostrils would use a slightly different air path then the swallowing mechanism, so that if you were to choke on food you could still breathe and get air into your lungs to expel the food.
Pretty sure those changes were made to get us better vocal cords, allowing us more range for speech. Here's the first link I found that talks about it.