How is Sakura a female Ryu, Sakura is socially well-adjusted and capable, she has one friendly rivalry with Karin, and many many friends including Dan, Blanka, Ibuki, Elena, and the Rival Schools trio (Hinata, Batsu, Shoma). Sakura also has a normie non-fighter bestie (Kei). Sakura is a productive member of society, she has a day job working in video game arcade. The writers have implied that one day she will work as PE teacher. She is also good with kids.
Meanwhile, Ryu is unhoused and jobless (by choice). He has no friend outside fighting and even among his fighting friends (Ken, Chun) he has no social skills.