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A new version of the popular diabetes treatment Mounjaro can be sold as a weight-loss drug, U.S. regulators announced Wednesday.

The U.S. Food and Drug Administration approved Eli Lilly's drug, named Zepbound. The drug, also known as tirzepatide, helped dieters lose as much as 40 to 60 pounds in testing.

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[-] generic@iusearchlinux.fyi 32 points 7 months ago* (last edited 7 months ago)

Manjaro? I use that on my computer!

Oh, you said Mounjaro? Never mind.

[-] sebinspace@lemmy.world 24 points 7 months ago
[-] Zozano@aussie.zone 10 points 7 months ago

Manjaro users don't have the superiority complex required to be this prude.

[-] ObviouslyNotBanana@lemmy.world 8 points 7 months ago

It's because they have no idea how their system actually works

This comment was made by the Real Arch Gang

[-] DarkenLM@kbin.social 7 points 7 months ago

I personally know a handful of people that also don't know how the fuck Arch works but still use it.

[-] ObviouslyNotBanana@lemmy.world 5 points 7 months ago* (last edited 7 months ago)

Yeah I was just kidding. I don't use it myself. Those people are everywhere though, I can confirm.

[-] DarkenLM@kbin.social 4 points 7 months ago

I figured.

Arch is great for people with a very extensive knowledge about the entire system, or for masochists. One wrong command and the whole thing catches on fire.

Respect for those who know how to use it and are not assholes about it, though.

[-] ObviouslyNotBanana@lemmy.world 3 points 7 months ago

Definitely. I've tried it, it wasn't my thing. I get it, but it's not for me.

[-] turbowafflz@lemmy.world 3 points 7 months ago* (last edited 7 months ago)

In my experience once you get it set up arch isn't that bad. I can only really remember one time it really broke and that was when my laptop ran out of battery during a kernel upgrade (I know I should have had it configured to keep multiple kernels but for some reason I didn't). I'm using opensuse a lot more recently though and it definitely is easier, just not by like an insane amount

[-] Zozano@aussie.zone 2 points 7 months ago

Getting Arch set up from scratch is a great learning experience. I recommend everyone to at least try to install it once properly, you'll definitely come away with a better understanding of the system.

[-] Zozano@aussie.zone 4 points 7 months ago

"I use Manjaro BTW"

("I use Manjaro, please don't bully me or ask me to use the terminal. Also, why hasn't Manjaro renewed their SSL certificate?")

[-] flicker@kbin.social 26 points 7 months ago

I'm on Wegovy and it's a miracle, frankly.

Between the ADHD medication wreaking havoc with my hunger signals and the non-diabetic hypoglycemia causing me to go from "not hungry" to "dying of a sugar crash," the Wegovy gave me actual satiety for the first time in my life, and evened out the crashes.

I'm a big fan of more options along these lines, for whoever they might save.

[-] SeaJ@lemm.ee 6 points 7 months ago

Unfortunately people gain the weight back once they stop taking the drug if there is no lifestyle change which there often is not. A guy I know owned a good chunk of Sequence which essentially fast tracked access to Wegovy through telehealth and working with insurance companies. He was pushing to partner with a company that could provide that lifestyle change info so that people could keep off the weight when they stop using it. Weight Watchers bought them so hopefully they can help provide that lifestyle change.

So far the side effects of Wegovy are fairly standard but it has only been around for 10 years and widely studied for an even shorter period since it has only been on the market for a couple years.

[-] flicker@kbin.social 1 points 7 months ago

I know that it's a lifelong drug. I don't care. I'll take it. Especially because of the evened out crashes! Not having a sugar high or a sugar low is so wonderful for someone who has spent 37 years enslaved to snacks.

[-] Revonult@lemmy.world 4 points 7 months ago

Okay so everyone is different but I just found out my non-diabetic hypoglycemia was almost entirly caused by my stimulant ADHD medication. I had been taking it for 12+ years and always thought the hypoglycemia was just how my body was, but it has been night and day. It was very hard to move away the the meds but but I know EXACTLY what you mean by the sudden "dying of sugar crash". Obviously the ADHD still needs treat but I will be moving to a non-stimulant for treatment.

[-] flicker@kbin.social 1 points 7 months ago

I'm upvoting you and I'm going to share your story with others but unfortunately I know this isn't the case with me, as I was adult diagnosis ADHD and dealt with the hypoglycemia since elementary school. I only tried stimulant medication for the first time two years ago.

But I wonder if any studies have been done about frequency of ADHD and hypoglycemia comorbidities! Seems promising!

[-] SuiXi3D@kbin.social 17 points 7 months ago* (last edited 7 months ago)

Ha! A grand a month. Fat chance.

[-] LordOfTheChia@lemmy.world 44 points 7 months ago* (last edited 7 months ago)

But it works. After paying for the med, you can no longer afford food for the month.

[-] SuiXi3D@kbin.social 7 points 7 months ago* (last edited 7 months ago)
[-] reluctantpornaccount@reddthat.com 5 points 7 months ago

The track record for weight loss drugs is not good. Even "approved" ones. We had a lot of teenagers on amphetamines to make them lose weight.

The podcast Maintenance Phase has at least one episode on them and their history.

[-] SeaJ@lemm.ee 10 points 7 months ago

The results for this and Wegovy are pretty promising. That said, the long term effects are unknown since they are so new. But the long term effects of having a BMI over 30 are pretty terrible and well known. These are nothing like amphetamines.

[-] ChexMax@lemmy.world -1 points 7 months ago

The results are that they were only tested on perfectly healthy people which is not indicative of their success in the general population, and the results were also that most people gained the weight back immediately upon stopping the drug.

The side effects were not too bad for people getting the drug for free, but at 1k a month, those side effects cause much higher drop out rates as well.

Still way more promising than anything else available, but not that promising overall.

[-] books@lemmy.world 7 points 7 months ago

Eh these people are either gonna be taking bp/cholesterol/diabetes medication or this. Seems like it has the potential to be a wash?

this post was submitted on 08 Nov 2023
166 points (97.7% liked)

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