Im actually a woman so I'd date that guy lmao

There are a variety of ways in which our bodies attune to constant stimulus, in the case of neural stimulus, there are a variety of mechcanisms with the common goal of reducing activation of the neural pathway. You could have less receptors, more breakdown of the stimulating compound, increased cell activation treshold or downstream changes that similarly just reduce the ability for the signal to cause effects further along the chain.

Receptor or physical clogging generally (afaik) does not happen with substances we encounter normally, however it is a common tactic in pharmacology, where we might use a drug that binds to a receptor without effect and prevents the active compound from binding.

Or in the case of Succinylcholine, it binds, causes the normal action, but then prevents the normal molecule from binding and causing the action again - this is used to achieve rapid muscle paralysis and is both a poison as well as a common drug used for anesthesia.

It's not all just negative tbh. I suffered from it myself and was an strict pescetarian before as I couldn't stand the taste of any meat besides fish.

Caught Covid and suddenly milk tastes like caramel and I started to enjoy the taste of beef and lamb. Coffee smells weird though, it triggers the same response in my brain as "A dog just pooped in the house two rooms over".

That last one is what annoys me. My sense of smell never relearned to distinguish those two things.

You can smell other people's mucous (not recommended). If you ever have been the primary care taker for a baby or small child you'd know what boogers smell like. Old boogers also start to decompose and the smell is faintly different. Sick mucous also smells different and worse. I could tell my nephews were sick with the flu by smelling them from ways away before noticing any other symptom. Sometimes I can smell that in public transport and it makes me figuratively run in the opposite direction of the sick person.