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I mean this is just dumb. Like I’m sorry but this would happen with basically every medicine or drug. They aren’t made to be taken at higher doses than advised.
(Imagine you took 8 liters of beer per day for 3 days, you’d be half dead too.)
Moderation people…
You haven't seen the ridiculous quantities that some alcoholics will consume
It's people like this who make other people think any amount of painkillers is bad, and seem to get a sense of superiority about them for never taking any.
My daughter's dog that is a climber got on a shelf and knocked a basket off that had a large bottle of Tylenol in it. She chewed the bottle up.
I got home and saw some pills and a demolished bottle on the ground. Vet tech friend said to induce vomiting with hydrogen peroxide.
Didn't have any of that, but I did have some minty mouthwash with peroxide and no xylitol in it. Dog willingly drank it, puked with foam, drank a bit more, puked more foam, then I dug through the mess.
No pills or any sign of the color on the pills. She's still kicking.
How big is a packet?
Off the shelf in the UK, they're sold in packs of either 8 or 16 tablets, and shops are legally only allowed to sell you two packs at once. Pharmacies can of course supply larger quantities with a prescription.
The recommended dose is one or two 500mg tablets every 4 hours with a maximum of 8 tablets per day.
Yeah, I think this is what's causing the confusion here. We don't measure pills in "packets" in the US, so I think some people are taking "4 packets" to mean that they only took four pills and of course that's absurd.
ITT: People who don't know the difference between acute and chronic ODs and how a smaller amount over a long period can hurt you. 325mg APAP x4 will not kill you short term.
The problem was taking it every day over a long period.
Its still fucking stupid though.
It's why in the UK shops won't sell more than 2 packets at a time. It's statistically reduced the amount of people killing themselves with them (intentionally or by mistake).
He's not the first one to 'kill his liver' with paracetamol/ acetominophen (tylenol). First case I recall, the person was taking tylenol nightly with a glass of wine. Here's some links on the current understanding of Liver injury and paracetamol:
Apparently it's not always overdosing: Paracetamol-induced hepatotoxicity at recommended dosage (https://onlinelibrary.wiley.com/doi/full/10.1046/j.1365-2796.2003.01097.x)
Acetaminophen-Induced Hepatotoxicity: a Comprehensive Update (https://pmc.ncbi.nlm.nih.gov/articles/PMC4913076/) "...in the United States, in particular, it accounts for more than 50% of overdose-related acute liver failure and approximately 20% of the liver transplant cases."
Risk Factors for Hepatotoxicity Due to Paracetamol Overdose in Adults (https://www.mdpi.com/1648-9144/57/8/752) "In the univariable analysis, significant hepatotoxicity risk factors were male gender, alcohol abuse, an ingested paracetamol dose, and a timespan from ingestion to hospital admission. The later one was the only significant risk factor in the multivariable model (adjusted odds ratio 1.08; 95% CI: 1.03–1.12)."
Paracetamol (acetaminophen) overdose and hepatotoxicity: mechanism, treatment, prevention measures, and estimates of burden of disease (https://pubmed.ncbi.nlm.nih.gov/37436926/) "Where data were available, we estimate that paracetamol is involved in 6% of poisonings, 56% of severe acute liver injury and acute liver failure, and 7% of drug-induced liver injury."
Understanding paracetamol-induced liver failure (https://link.springer.com/article/10.1007/s00134-014-3293-9)
How much is a "packet"? edit: never mind, I found several conflicting answers in the other comments, no need to add even more and add to the confusion.