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Why some viral infections appear to trigger autoimmune disease (www.sciencedaily.com)

submitted 1 month ago by Bampot@lemmy.world to c/dangerdust@lemmy.world

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Chikungunya virus (CHIKV) is a mosquito-borne pathogen that has been identified in more than 110 countries around the world. The virus typically causes flu-like symptoms, but it can also trigger chronic, severe joint pain in some people.

The researchers found that 87 percent of patients had detectable levels of CHIKV-specific memory CD4+ T cells in their blood six years after their initial infection. In contrast, only 13 percent of patients still had CHIKV-specific memory CD8+ T cells in their blood after six years.

According to Weiskopf, this kind of CD4+ T cell profile is more commonly seen in patients with autoimmune diseases.

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