Ondansetron
Nauseous? You won't be for long if you take ondansetron.
this post was submitted on 06 Dec 2023
6 points (58.3% liked)
Ask Lemmy
27027 readers
797 users here now
A Fediverse community for open-ended, thought provoking questions
Please don't post about US Politics. If you need to do this, try !politicaldiscussion@lemmy.world
Rules: (interactive)
1) Be nice and; have fun
Doxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can't say something nice, don't say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. Please familiarize yourself with them
2) All posts must end with a '?'
This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?
3) No spam
Please do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.
4) NSFW is okay, within reason
Just remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either !asklemmyafterdark@lemmy.world or !asklemmynsfw@lemmynsfw.com.
NSFW comments should be restricted to posts tagged [NSFW].
5) This is not a support community.
It is not a place for 'how do I?', type questions.
If you have any questions regarding the site itself or would like to report a community, please direct them to Lemmy.world Support or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.
Reminder: The terms of service apply here too.
Partnered Communities:
Logo design credit goes to: tubbadu
founded 1 year ago
MODERATORS
Heads up to anyone with cardiac issues, especially long QT syndrome or other meds that prolong the QT internal: Ondansetron is so notorious for QT prolongation and cardiac arrhythmia problems that we have to perform an EKG before we're allowed to give you a second dose on our cardiac unit.
I have scary anecdotes that bias me against it lol
A relatively niche case, to be sure, but thank you for pointing it out.
Yeah, long QT syndrome is estimated around 1/2000 people. Relatively rare. I fully confess that I'm just traumatized by my personal experiences with patients taking the drug lol
load more comments
(1 replies)
My wife has been on 8mg twice daily (oral dissolving and tabular at different times) + domperidone and it’s still not altered a chronic nausea that started at pregnancy. Little ones second birthday in a week, not a day without throwing up within minutes of eating or drinking anything at all - paramedics called it a starvation diet.
Not that there’s anything you can do, just getting increasingly desperate and throwing this out there in case anyone has anything to relate to this.
Super glad it’s working for you though - it’s a wonder drug for so many people!
Has she ever tried cannabis, don't like cancer patients often find it helpful enough for their purposes? Any ideas as to the etiology of her conditon?
?Like, did the pregnancy flip some kind of epigenetic/latent switch of some sort?
load more comments
(15 replies)
Sorry it's not working for her! I think pregnancy might be a special type of nausea that's a little harder to treat.... I know ondansetron is commonly given to cancer patients and it's enough for many of them and not enough for others. For those of us with more mundane nausea, it really is a miracle drug.
I hope she find something that helps her or she gets past the nausea stage soon. And congratulations on the upcoming family addition.
Pregnancy is a beast! We’re lucky he’s already with us, almost turning 2! Still sick however, curiously for a few minutes immediately after birth she felt 100% better but that came back permanently the instant she started to breastfeed the first time.
Thanks for your well wishes! Best to you.
I am so sorry that she's dealing with this. I've heard of successful treatment of intractable nausea using biofeedback therapy. The idea being that the body gets stuck in a negative feedback loop and trying to reverse that back to previous functioning.
I hope this gets better for her.
Thank you!! I’ve been convinced it’s a negative feedback loop myself but I’ve not been able to find anything worthwhile on this. This is super and I’ll be taking a close look tonight to add this to my Zotero library. I’ve been shut down by doctors before on cyclic vomiting syndrome but this looks very promising and worth a shot for sure especially with that shared etiology.
Take care!
Yeah, medically cyclic vomiting syndrome is usually more associated with cannabis abuse disorder, so you're probably not going to get far trying to get that diagnosis specifically. But that doesn't mean these same treatment regimens won't help. Think of it as physical therapy for the gut and nervous system.
load more comments
(2 replies)
load more comments
(2 replies)
Apigenin (herbal supplement)
Insomnia, anxiety
Derived from chamomile flowers (and other plant sources), I've found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I've tried them all.)
Was curious about this since Andrew Huberman mentioned it
It's really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you'll see advertised. I only mention because I think the standard advertised range is probably too low for people like me.
Thanks! Is it expensive? How much do you get?
Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha
I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
Is that the dose, 1/night before bed?
Yep, that's the usual recommended dose - 200mg like an hour before bedtime
Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she'd be into it
load more comments
(14 replies)
Coenzyme Q10
Energy, mitochondrial support, antioxidant
Personally, I think everyone should be taking this. Extremely safe, improves cardiac outcomes, some evidence that it can reverse damage in chronic kidney disease. Most people won't feel different, but I take high dose CoQ10 for mitochondrial dysfunction, and I can tell you it definitely has a huge impact. Love this stuff.
Phenibut
Helps relieve anxiety and eases social contact. For me personally its just a mood enhancer and makes listening to music so good. About 500-1500mg is a normal dose, lasts for up to 24h and should not be taken more often than once a week.
load more comments
(2 replies)
Pregabalin (Lyrica)
Fascinating medication that I have found to annihilate anxiety (excellent anxiolytic) and promote social cohesion/sociabillity/oversharing beware. Takes the edge of stimulants as well
Almost like a pharmaceutical slightly sedative-leaning version of ecstasy but obviously quite distinct pharmacologically and not a replacement for same.
view more: next ›