Change that double helix into a quadruple one for extra redundancy, making it harder for it to gain irreparable damage. Also, make it a loop rather than a straight line so the ends don't get shorter with each replication. And remove that dementia bug that has a greater chance of showing up the longer run time is
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Sounds good. Not sure this counts as a minor change...
Stop aging at 20
The ability to turn off some senses temporarily
I'd like extra thumbs please
For this one there's actually technology in development right now.
Better repairing, see Deadpool. Cancer, missing limbs, teeth, w/e.
Would complete immunity to radiation be a small change?
Would it actually be detrimental in the long run?
Pros: No more cancer
Cons: No more natural evolution
Make a full night's sleep like 4 hours or something. As long as our corporate overlords don't take advantage and make it a 12 hour workday.
Maybe body odor could be an opt-in? For, like, sexy times between men who like that kind of thing...
A utility panel with usb ports, hard reset button, xd card slot, s-video port, etc, could be very useful.
Maybe installed on a butt cheek or back of a calf?
In all seriousness, a spinal realignment feature. Something that resets the joints & muscles in your back to factory default.