Lemmy Today

1,906 readers
110 users here now

Welcome to lemmy.today!

About us

🤗 Thanks for joining our little instance here, located in Oregon. The idea is to have a fast, stable instance and allow users to subscribe to whatever content they want from here.

😎 We dont block any other instances. We will keep it that way unless it becomes a moderation problem.

🤠 We will be around for a very long time, so you dont have to worry about us shutting down the instance anytime soon. We like performance and stability in our servers, and will upgrade the instance when its needed.

🥹 Make sure to join a lot of remote communities to get a good feed going. How to do that is explained here.

Lemmy mobile apps

You should start using one of these ASAP since the web browser user interface is quite ugly, even with themes.

Sync for Lemmy (Android)
Boost for Lemmy (Android)
Eternity (Android)
Liftoff (Android and IOS)
Voyager (IOS)
Voyager WebApp
Jerboa (Android)
Connect (Android)
Thunder (Android and IOS)
Mlem (IOS)
Memmy (IOS)

Optional Lemmy web browser user interfaces

Rules

Be respectful. Everyone should feel welcome here.
No bigotry - including racism, sexism, ableism, homophobia, transphobia, or xenophobia.
No Ads / Spamming, or creating communities to promote blogs or services.
No local pornography communities (but you are free to subscribe to them on other instances if you wish).
No local communities about software related to porn.
No local religious communities (use remote ones)

Contact the admin

@mrmanager

founded 2 years ago

ADMINS

mrmanager

Buelldozer

DNA fragments detected in monovalent and bivalent Pfizer/BioNTech and Moderna modRNA COVID-19 vaccines from Ontario, Canada: Exploratory dose response relationship with serious adverse events. (osf.io)

submitted 1 year ago by fluid_neutral to c/science@kbin.social

0 comments fedilink

...we found preliminary evidence of a dose response relationship of the amount of DNA per dose and the frequency of serious adverse events (SAEs). This relationship was different for the Pfizer and Moderna products. Size distribution analysis found mean and maximum DNA fragment lengths of 214 base pairs (bp) and 3.5 kb, respectively. The plasmid DNA is likely inside the LNPs and is protected from nucleases. Conclusion: These data demonstrate the presence of billions to hundreds of billions of DNA molecules per dose in these vaccines. Using fluorometry, all vaccines exceed the guidelines for residual DNA set by FDA and WHO of 10 ng/dose by 188 – 509-fold...

-15

submitted 1 year ago by fluid_neutral to c/science@lemmy.world

5 comments fedilink

Results: ... we found preliminary evidence of a dose response relationship of the amount of DNA per dose and the frequency of serious adverse events (SAEs). This relationship was different for the Pfizer and Moderna products. Size distribution analysis found mean and maximum DNA fragment lengths of 214 base pairs (bp) and 3.5 kb, respectively. The plasmid DNA is likely inside the LNPs and is protected from nucleases. Conclusion: These data demonstrate the presence of billions to hundreds of billions of DNA molecules per dose in these vaccines. Using fluorometry, all vaccines exceed the guidelines for residual DNA set by FDA and WHO of 10 ng/dose by 188 – 509-fold...