this post was submitted on 30 Dec 2024
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First month of pills? I thought esketamine was only approved as a nasal spray.
There’s a phase 2 trial from this summer, but idk if it’s been approved yet.
https://www.nature.com/articles/s41591-024-03063-x
Someone correct me if I’m wrong but they may be enrolling you in a clinical trial, for which you should be paid.
I think they're doing legal loophole fuckery with the blessing of a corrupt or lazy physician. I've seen it with other substances and it can be a trainwreck for legitimate research progress. I'm actually kind of alarmed to be hearing about this sort of operation.
If it’s not a clinical trial idk how they’re doing this, legally speaking. I do recreational drugs, but this ain’t that, and there’s procedures and laws to follow. Sometimes those procedures are exploited by companies for profit, but at their base they are there to protect the public from those same companies.
FYI, a friend shared this, it links to actual papers. It sounds like the product being offered here. I haven't read enough yet to know if any of this has gone past clinical trial stages, but you are dead right that Corgi is probably entitled to receive compensation if this is a trial. Could that be the loophole and they're just counting on ignorance or some corporate / marketing construct to launder the trial / fast-track putting the formulation onto the market for a purely profit driven motive?
https://www.osmind.org/blog/sublingual-ketamine-troches-for-home-use-an-evidence-based-introduction-part-1
Friend also suggested that some of the links may be inaccurate, so I suppose further digging would be required to match paper titles with their papers in the usual databases. Obviously "osmind.org" doesn't hit with a lot of authority.
Yeah they do quote a fair amount of studies in there but it’s late for me to scan several studies. I posted this earlier but this is probably the highest quality trial that is working towards approval for oral ketamine for depression
https://www.nature.com/articles/s41591-024-03063-x
Not even close to daily dosing, as has been shown previously with esketamine (monthly) to be far more effective.
Yup. I think the concern displayed by all in this thread is valid and appropriate given what's been properly studied.
Appreciate the summary/abstract. I'm getting into the NYE spirit right now and have been posting on and off all day so my capacity to read studies and grok them is diminished.
I'm sure we'll be reading about the details in the alternative press and then mainstream news within the next couple of years after a bunch of burnout casualties result from this.
They told me it's actually a lozenge or cough drop type thing, but that isn't really important to the thread