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Gambling: Legal gambling doesn't stop illegal gambling. Like dog fights, cock fights (which--disappointingly--involve chickens), or people that are out of money and credit; they're still going exist. It would be healthier for society to make gambling unpopular, rather than squeezing every last bit of revenue out people that usually can't afford it.
Prostitution: Legalizing under the Nevada model does nothing to illegal prostitution, because the Nevada model puts it out of financial reach for most of the clientele and restricts the locations to places that the clientele usually aren't (e.g., they're a long way out of the city, and you have to drive several hours from Vegas to get to the closest one). An (illegal) independent escort in Las Vegas will typically cost $350-500 per hour, and quite possibly far, far more. A sex worker at a legal brothel will easily cost more than $1000 for the same time period. A sex worker controlled by a pimp is going to be $200 or less, and have less ability--or no ability--to refuse acts that s/he doesn't want to do. The cost of compliance with regulations is on the sex worker, who passes it on to the clientele; that regulatory model means that legal avenues will end up being less affordable to people than illicit avenues. (And, given that you can pretty easily find escorts working in Vegas despite legal options being available in the state, I think it's pretty clear that people will be price sensitive.
Drugs: Same issue. Regulatory oversight--which is necessary for recreational drugs to not kill people unintentionally--increases costs, and those costs get passed to the consumer. For a very real-world example, a single 10mL vial of 200mg/mL testosterone cypionate costs about $60 at Costco, and over $100 at Walgreens, et al.. (Testosterone cypionate is a schedule III drug.) You can buy a 20mL vial of 300mg/mL testosterone cypionate on the black market for anywhere from $30-60. You can buy raw hormone powder for under $2/gram (e.g., the raw hormone used in the black market 20mL vial costs the producer $12 or less). A therapeutic dose will be perhaps 150-200mg/week, depending on your own physiology, and what you're target blood values are. An IFBB pro bodybuilder is going to go through a minimum of 3,000 mg/week during a bulk. If an IFBB pro were to buy their testosterone cypionate legally--if they didn't need a prescription--it would cost $90/week, versus $15-30. (This ignores all the other shit they take, too.) IFBB guys have been using their black market suppliers for years, maybe decades; what's their incentive to pay 3-6x as much for something they aren't going to see a difference in? Legal marijuana has depressed prices for illegal marijuana, but it's still cheaper to buy a quarter from my local guy than it is to buy in a dispensary.
Organized crime makes a fuckton of money by forging tax stamps on cigarettes to evade taxes. Before prices started going up dramatically on cigarettes (which I think was a good thing, since smoking doesn't end up costing just the smoker), that kind of fraud and tax evasion was chump change. Now it's millions.