Helldivers 2

Quasar has a permanent slot in my strategem loadout now. At least, until it gets nerfed, which I have a very strong feeling that it will.

On the bug side it one-shots Hive Guards through their armor, one-shots Chargers to the face, and two-shots Bile Titans to the face. On the bot side it pretty much one-shots everything if you hit the weak point; I've yet to see anything survive a direct shot to the vents. It even takes out Bot Drops with a single shot to the engine; if you coordinate it with your team and they're paying attention, you can easily nullify an entire bot reinforcement before they even touch the ground.

It also puts in work against structures, too; easily takes out spore towers, turret towers, fabricators, illegal broadcasts, all from insanely safe distances. I haven't tested it against Shrieker nests or bot artillery, but I can't think of any reason why it wouldn't also put in work on these, as well. It works but it's not super useful against bug holes or eggs, but both of those are easily covered by your primary/grenades, anyway.