Opening the vault door, seeing your first half-robot/half-mutant, and trying to figure out if it's real or you're just high on Vault-Tec Patented Meat Slurry again:

Fun fact, the Stanford Prison Experiment was actually kind of a joke! Zimbardo really wanted the result that he got, and interfered with the "study" to ensure that he got it. People aren't as easily predisposed to evil as he wanted us to be.

Kinda goes against the theme of the setting, but what if one of the vaults was successful in experimenting on humans genetically or something.

Would be cool to be a master chief style Spartan looking dude coming out of the vault in a more fucked up area and bringing down the hammer.

I just like the idea of mixing it up lol.

Ok I am a guy and I always wonder how the vault was with the one guy and the rest ladies

this one is for laughs and giggles. I mean we will randomly pump small amounts of laughing gas into the vents and see if it improves morale.