Games

Shane’s 6-heart cutscene on the cliff in Stardew Valley.

Also the very last story moments of Tears of the Kingdom. The dive reach grab bit.

I got all fucked up inside when Agro died in Shadow of the Colossus.

Stray ending

More of a playable story, but the entirety of Dear Esther is a bit heart wrenching.

There have actually been a lot of games that have made me cry over they years. Some of the ones I remember are:

Metal Gear Solid 1, 2, 3 and Peace Walker

Kingdom Hearts 1, 2, BBS, Re:Coded and 358/2 days

Final Fantasy 10 and (obviously) Crisis Core

Castlevania Order of Ecclesia

I'm pretty sure there are more but I can't really remember any others. I've kind of always been very sensitive to emotional things, so a lot of games get at least a tear or two but the ones I mentioned were games that I remember being wrecked after playing.

Brothers. Damn ending making me feel empty…

Borderlands 2, the ending of the Tiny Tina DLC.

Damn near everything in Nier Gestalt/Replicant. That game wrecks me every time I play it.

Fallout: New Vegas.

At the end of Boone's companion quest, we're watching the sunrise, having barely survived the night. He confesses what really happened to his wife. Nat King Cole comes on the radio with "Love Me." I weep.

I was pretty emotionally stunted and depressed as a teenager and had trouble crying even when I wanted to (it's a horrible feeling, physically) so Earthbound and Mother 3 were therapeutic

Life is strange. Repeatedly.

No spoilers but the ending of Life Is Strange made me cry.

The first time was in Mass Effect 3, when Liara shows you her project in your cabin. For me, this was the first time in the trilogy where I felt that we could really lose the war against the reapers.

Another very good moment was in Life is Strange Before the Storm, when Chloe finds her dad's car in the junkyard. That hit hard.

Mafia 1. "Mr. Salieri sends his regards". Need I say more?

Mass Effect 3: "Leaving Earth"

ME:3 and the cliff.

Several points in Life is Strange, I have yet to finish that game.

FFXIV, over and over. The kind of nobility and self sacrifice displayed in that story has set me crying several times. Honestly, I can feel it a little bit just thinking of some of those moments, but I try to smile through it.

Because a smile better suits a hero.

The ending of Legend of Zelda Tears of the Kingdom, it was just so cool and and so well done. What a great final boss when compared to Breath of the wild.

Hl2 EP2's ending

I tried to install Skyrim and my disc was unreadable

Pretty much everything in The Last of Us Part 1 & 2.

The entire "What Remains of Edith Finch" game

Before your eyes

Game that uses your blinking as it's controls

Ending just had me in tears

Getting the True Ending in the base game of Outer Wilds. Including the credits, including after the credits. So beautifully bittersweet.

Beginning of last of us part 1.

Ori and the Will of the Wisps has some great emotional moments that are complemented by a fantastic soundtrack. Learning about Shriek's backstory after being hunted by her the entire game was just too much.

the end of season 1 of the walking dead game. goddamn what a gut punch

Horizon zero dawn is the game that got me. Getting closer to the end just got me sadder and sadder.

A weird one that I've not seen mentioned: the intro to Battlefield 1. It is really well crafted and was emotional in a way I've never felt from a war FPS.

The multiple unavoidable deaths and brief epitaph shown on screen, before hot swapping to the next soldier felt poignant. Really hit me with the pointlessness and futility of WWI, the plight of the common soldier and the sheer scale of death.