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FDA says common over the counter decongestant phenylephrine does not work in oral form
(www.nbcnews.com)
this post was submitted on 12 Sep 2023
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You know what's weird? I get severe sinus headaches and regular pseudoenepherine sudafed doesn't help at all, but these phelylephrine ones do. I'll even tell my wife "the little reds, not the whites". Weird.
Have you tried a migraine formulation for that? It sounds like you're actually benefiting from the systemic effects (vasoconstriction) instead of the reduced mucous production. A formulation would include caffeine that also has vasoconstriction in case this is removed from the market.
Interesting, I'll take a look
The real pseudoephedrines are also little red pills, at least where I am on the US East Coast.
Weird, here in my area of California the OTC ones are the reds, you have to go to the pharmacist for the white ones.
In my area both are red unless you get the 12-hour controlled-release caplets, those are white. It's probably just different factories.
It depends on the dosage. The 4hr pseudoephedrine are red. The 12hr are white.
I forget but wasn't it also advertised to have a painkilling effect? Maybe the thing it's doing for you isn't the decongestant but that?
In my area the red ones are the pseudophedrine ones. Never seen the white ones, I just go to the counter because I am not making meth.
Weird, there are what I get in northern California
The power of placebo! It's the nicest part about placebo too. The more you believe it the more your body does too.
I actually doubt that. Phenylephrine does have systemic effects that might be beneficial for migraines. That's not what it was decided to not be effective in with the FDA and not what folks generally use it for. Pseudoephedrine isn't really that effective for migraines itself.
Nah, the drug is still a bio-active drug. It DOES do things, just doesn't help most with the prescribed symptoms because its mechanism of effect is different.
No.... You just spend more money on things that don't work while convincing yourself that it does.
When I had COVID and got really severe congestion, it was some of the worst sinus pain I've ever had in my life. I was at the point where I was trying to use a baby nasal bulb to relieve some pressure. The phenylephrine helped me a lot more than any other medication I was trying, including nasal sprays. I also take other sinus medications though, so I wonder if it's a case of a medication not working well unless it's used in conjunction with other things?
I guess it's possible I experienced a placebo effect, but it seems weird it would do it when nothing else was.