this post was submitted on 21 Jul 2025
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My child had to switch from Medikinet removed to the Zentiva version. Teachers said the generic is hardly working at all.

Can it really be so much different? Both claim to have a 50 % instant-release part.

Medikinet removed has a similar curve as Ritalin LA with a stronger peak between hour 3 and 6. The Zentiva isn't even documented that well. German article with interesting comparison graphs: https://www.ppt-online.de/heftarchiv/2022/04/individuelle-adhs-therapie-mit-methylphenidat-removedpraeparaten.html

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[–] can@sh.itjust.works 9 points 1 week ago (2 children)

My child had to switch from Medikinet removed to the Zentiva version. Teachers said the generic is hardly working at all.

Unrelated to your question, but please, I need to know what word dot ml decided to filter out lol

[–] TherapyGary@lemmy.blahaj.zone 10 points 1 week ago* (last edited 1 week ago) (1 children)

The "r word" (retard) as in slow release

[–] can@sh.itjust.works 8 points 1 week ago* (last edited 1 week ago)

Of course

Edit: they'll filter it even if you're french

[–] otter@lemmy.dbzer0.com 2 points 1 week ago

Same. "XR"?

[–] KittenBiscuits 8 points 1 week ago (2 children)

Generic extended release methylphenidate was what my primary care doc first tried me on. I noticed it a little and thought ok, it's still really hard to function. What do people mean that getting on medication was a game changer for them?

After about a year of this, trudging through my day still, I got in to see a psych about a month ago who switched me to Vyvanse, and holy cow. I'm functioning again! Wtf?!

I will say that my sleep has suffered some, but that's a little bit on me for not taking my meds early enough in the day.

[–] spankmonkey@lemmy.world 3 points 1 week ago* (last edited 1 week ago)

It is funny because Vyvanse gave me weird side effects without any benefit (too long ago to remember) while the ER methylphenidate had a progressively more effective benefit with zero side effects for me as the dosage went up to the one I settled on. Been taking it for years and have to justify to insurance once a year that no, I don't want to try the ones that didn't work just let me stay on this.

Glad to hear you found one that works for you!

[–] ryannathans@aussie.zone 3 points 1 week ago

You can try something like 1mg extended release melatonin for sleep

[–] superduperpirate@lemmy.world 5 points 1 week ago

Looks like the post is referring to a Medikinet product that could also be described as delayed release or modified release, instead of the word which was censored in the post. In case anyone else was confused like me.

[–] spankmonkey@lemmy.world 3 points 1 week ago

I am on the extended release (ER) for methylphenidate on a high dose for like 20 years and for me it lets me focus while it is working.

Sustained release (SR) does not work nearly as well for me. Standard release wears off way too fast.

People have very different rates of success or side effects so yes, it really could be that different! It sounds like this isn't the right one for your kiddo.

[–] Siethron@lemmy.world 2 points 1 week ago

Adult on time release generic methylphenidate here. I notice it usually starts working about 45 minutes after ingestion. Instant release only really means as soon as it begins to be digested and everybody's body is different.

Also remember, don't mix it with caffeine or the effects will be greatly reduced.