crossposted from: https://lemmy.blahaj.zone/post/29702037

transcription: disembodies hand: "pspsps" buff catgirl: "the fuck you say punk!"

Background

Collagen supplements are promoted to help aging skin. However, no meta-analysis of randomized controlled trials (RCTs) has examined their effects by funding source and study quality, which may influence outcomes.

Methods

PubMed, Embase, and Cochrane Library were searched from inception to June 14, 2024.

Results

A total of 23 RCTs with 1474 participants were analyzed. In a meta-analysis of all 23 RCTs, collagen supplements significantly improved skin hydration, elasticity, and wrinkles. However, in the subgroup meta-analysis by funding source, studies not receiving funding from pharmaceutical companies revealed no effect of collagen supplements for improving skin hydration, elasticity, and wrinkles, while those receiving funding from pharmaceutical companies did show significant effects. Similarly, high-quality studies revealed no significant effect in all categories, while low-quality studies revealed a significant improvement in elasticity.

Conclusions

There is currently no clinical evidence to support the use of collagen supplements to prevent or treat skin aging.

Some games vanish. Not because they broke the law but because someone decided they shouldn’t exist.

For 48 hours, these games are free, because if a game is legal, you should be free to buy it

• POSTAL 2
• Agony + Agony UNRATED
• Leap of Love
• Being a DIK - Season 1
• Leap of Faith
• House Party
• HuniePop
• Lust Theory
• Treasure of Nadia
• Summer's Gone - Season 1
• Fetish Locator Week One
• Sapphire Safari
• Helping the Hotties

For all of President Donald Trump’s promises of an economic “golden age,” a spate of weak indicators this week told a potentially worrisome story as the impacts of his policies are coming into focus.

Changing Cities haben ein Tool entwickelt, mit dem Unfälle und Unfallhäufigkeiten an Straßen und Kreuzungen analysiert werden können. Eine interaktive Karte auf Basis der Daten das Unfallatlas zeigt Unfälle je nach Schwere, Beteiligten und Ort, filterbar nach Jahr, Uhrzeit oder Wochentag.

Auf Grundlage dieser Daten können gefährliche Straßen oder Kreuzungen identifiziert und Behörden zum Handeln bewegt werden – im Sinne der #VisionZero: keine Verkehrstoten oder Schwerverletzten mehr.

Dafür enthält die Seite eine Mailvorlage für ein Anschreiben an die zuständige Behörde, um diese zu konkreten Maßnahmen (z.B. Tempo 30, sichere Rad- und Fußwege, Einschränkungen des fließenden und ruhenden Kfz-Verkehrs) aufzufordern.

“Jujutsu (jj) is a version control system with a significantly simplified mental model and command-line interface compared to Git, without sacrificing expressibility or power (in fact, you could argue Jujutsu is more powerful). Stacked-diff workflows, seamless rebases, and ephemeral revisions are all natural with jj [...]”

Part 2 of the series is out and is here.

Over 250,000 people suffered domestic violence in Germany last year, according to a media report citing official figures.